CYP3A4 polyclonal, anti-mouse

Background:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase.

Synonyms: CYP3A3, CYPIIIA3, CYPIIIA4, Cytochrome P450 NF-25

Cellular Location: Cytoplasm Cell membrane

Immunogen:
A synthetic peptide of human CYP3A4

Gene Symbol: CYP3A4

Gene ID: 1576

Swiss prot: P08684

Calculated MW: 57kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.