CYP3A5 polyclonal (C-term), anti-human

CYP3A5 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP7794b
Catalog Number: AC-AP7794b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB15796
Applications: WB, IF, IHC-P
Datasheet

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Background:
CYP3A5 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione.

Other Names:
Cytochrome P450 3A5, CYPIIIA5, Cytochrome P450 HLp2, Cytochrome P450-PCN3, CYP3A5

Target/Specificity:
This CYP3A5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-502 amino acids from the C-terminal region of human CYP3A5.

Antigen Region:
476-502

Antigen Type: Synthetic Peptide

Gene Name: CYP3A5 {ECO:0000303|PubMed:8569713, ECO:0000312|HGNC:HGNC:2638}
Gene ID: 1577
Primary Accession: P20815
NCBI Accession: NP_000768.1;NP_001177413.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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