CYP46A1 antibody (clone 1A11), anti-human
€435.00
In stock
SKU
AC-AT1705a
Catalog Number: AC-AT1705a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
Request Information AC-AT1705a">Request Information
Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.
Other Names:
Cholesterol 24-hydroxylase, CH24H, Cytochrome P450 46A1, CYP46A1, CYP46
Antigen Type:
Recombinant Protein
Gene Name: CYP46A1 {ECO:0000303|PubMed:20667828, ECO:0000312|HGNC:HGNC:2641}
Gene ID: 10858
NCBI Accession: NP_006659.1
Primary Accession: Q9Y6A2
Other Accession: NM_006668
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.
Other Names:
Cholesterol 24-hydroxylase, CH24H, Cytochrome P450 46A1, CYP46A1, CYP46
Antigen Type:
Recombinant Protein
Gene Name: CYP46A1 {ECO:0000303|PubMed:20667828, ECO:0000312|HGNC:HGNC:2641}
Gene ID: 10858
NCBI Accession: NP_006659.1
Primary Accession: Q9Y6A2
Other Accession: NM_006668
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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