CYP46A1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71294
Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.
Alternative Name:
CP46, CYP46
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: CYP46A1 polyclonal antibody detects endogenous levels of CYP46A1 protein.
Immunogen:
Recombinant protein of human CYP46A1.
MW: ~ 57 kDa
Swis Prot.: Q9Y6A2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.
Alternative Name:
CP46, CYP46
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: CYP46A1 polyclonal antibody detects endogenous levels of CYP46A1 protein.
Immunogen:
Recombinant protein of human CYP46A1.
MW: ~ 57 kDa
Swis Prot.: Q9Y6A2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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