CYP51A1 Polyclonal Antibody

Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Cardiovascular, Metabolism, Signal Transduction

Synonyms:
CYP51A1, CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1, CYP51A1

Immunogen: Recombinant fusion protein of human CYP51A1 (NP_000777.1).

Swissprot: Q16850
Gene ID: 1595

Calculated MW: 46 kDa/56 kDa
Observed MW: Refer to figures

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.