CYP5A1 polyclonal (Center), anti-mouse

CYP5A1 polyclonal (Center), anti-mouse

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In stock
SKU
AC-AP12077c
Catalog Number: AC-AP12077c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB17080
Applications: IHC-P, WB
Datasheet

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Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Other Names:
Thromboxane-A synthase, TXA synthase, TXS, Cytochrome P450 5A1, TBXAS1, CYP5, CYP5A1

Target/Specificity:
This CYP5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-257 amino acids from the Central region of human CYP5A1.

Antigen Region:
226-257

Antigen Type: Synthetic Peptide

Gene Name: TBXAS1
Gene ID: 6916
Primary Accession: P24557
NCBI Accession: NP_001052.2;NP_001124438.1;NP_001159726.1
Other Accession: Q2PG45; Q2KIG5; NP_001052.2; NP_001124438.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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