CYP7B1 antibody (clone 2B11), anti-human
€435.00
In stock
SKU
AC-AT1706a
Catalog Number: AC-AT1706a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
Request Information AC-AT1706a">Request Information
Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.
Other Names:
25-hydroxycholesterol 7-alpha-hydroxylase, Cytochrome P450 7B1, Oxysterol 7-alpha-hydroxylase, CYP7B1
Antigen Type:
Recombinant Protein
Gene Name: CYP7B1 {ECO:0000303|PubMed:24491228, ECO:0000312|HGNC:HGNC:2652}
Gene ID: 9420
NCBI Accession: NP_004811.1
Primary Accession: O75881
Other Accession: NM_004820
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.
Other Names:
25-hydroxycholesterol 7-alpha-hydroxylase, Cytochrome P450 7B1, Oxysterol 7-alpha-hydroxylase, CYP7B1
Antigen Type:
Recombinant Protein
Gene Name: CYP7B1 {ECO:0000303|PubMed:24491228, ECO:0000312|HGNC:HGNC:2652}
Gene ID: 9420
NCBI Accession: NP_004811.1
Primary Accession: O75881
Other Accession: NM_004820
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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