CYSLTR1 polyclonal (Center), anti-human

CYSLTR1 polyclonal (Center), anti-human

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In stock
SKU
AC-AP14813c
Catalog Number: AC-AP14813c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34401
Applications: IHC-P, WB
Datasheet

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Background:
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.

Other Names:
Cysteinyl leukotriene receptor 1, CysLTR1, Cysteinyl leukotriene D4 receptor, LTD4 receptor, G-protein coupled receptor HG55, HMTMF81, CYSLTR1, CYSLT1

Target/Specificity:
This CYSLTR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-172 amino acids from the Central region of human CYSLTR1.

Antigen Region:
144-172

Antigen Type: Synthetic Peptide

Gene Name: CYSLTR1
Gene ID: 10800
Primary Accession: Q9Y271
NCBI Accession: NP_001269115.1;NP_001269116.1;NP_001269117.1;NP_006630.1
Other Accession: NP_006630.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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