Cystatin 9L2 (F87) polyclonal, anti-human, mouse, rat

Background:
Cystatin 9 (CST9) is a member of the type 2 cysteine protease inhibitor family, which has been shown to have immunomodulatory effects that restrain inflammation. rCST9 induced autophagy in macrophages via the regulation of the mammalian target of rapamycin (mTOR) signaling pathways. rCST9 promoted the upregulation of macrophage proteins involved in antiinflammation and antiapoptosis, while restraining proinflammatory-associated proteins.

Alternative Name:
Putative cystatin-9-like protein CST9LP1, Cystatin-9-like pseudogene 1, CST9LP1

Application Dilution:
WB: 1:500~1:1000

Specificity: Cystatin 9L2 (F87) polyclonal antibody detects endogenous levels of Cystatin 9L2 protein.

Immunogen:
Synthetic peptide, corresponding to amino acids 57-117 of Human Cystatin 9L2.

MW: ~ 17 kDa

Swiss-Prot: Q5W188

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.