Cystatin C (clone 6F12-C7-D8), anti-human

Background:
Cystatin C or cystatin 3 (formerly gamma trace,post-gamma-globulin or neuroendocrine basic polypeptide),[2] a protein encoded by the CST3 gene,is mainly used as a biomarker of kidney function.Recently,it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease.It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition),such as Alzheimer's disease.In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids.It is found in virtually all tissues and body fluids.It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes).Cystatin C belongs to the type 2 cystatin gene family.

Synonyms: ARMD11, HEL-S-2

Cellular Location: Secreted

Immunogen:
Recombinant human cystatin c protein.

Gene Symbol: Cystatin C

Gene ID: 1471

Swiss prot: P01034

Calculated MW: 13kDa

Recommended dilution:
WB 1:1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.