CYTH1 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP14202a
Background:
The protein encoded by this gene is a member of the PSCDfamily. Members of this family have identical structuralorganization that consists of an N-terminal coiled-coil motif, acentral Sec7 domain, and a C-terminal pleckstrin homology (PH)domain. The coiled-coil motif is involved in homodimerization, theSec7 domain contains guanine-nucleotide exchange protein (GEP)activity, and the PH domain interacts with phospholipids and isresponsible for association of PSCDs with membranes. Members ofthis family appear to mediate the regulation of protein sorting andmembrane trafficking. This gene is highly expressed in naturalkiller and peripheral T cells, and regulates the adhesiveness ofintegrins at the plasma membrane of lymphocytes. The encodedprotein is 83% homologous to that of CYTH2.
Other Names:
Cytohesin-1, PH, SEC7 and coiled-coil domain-containing protein 1, SEC7 homolog B2-1, CYTH1, D17S811E, PSCD1
Gene Name: CYTH1 (HGNC:9501)
Gene ID: 9267
Primary Accession: Q15438
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a member of the PSCDfamily. Members of this family have identical structuralorganization that consists of an N-terminal coiled-coil motif, acentral Sec7 domain, and a C-terminal pleckstrin homology (PH)domain. The coiled-coil motif is involved in homodimerization, theSec7 domain contains guanine-nucleotide exchange protein (GEP)activity, and the PH domain interacts with phospholipids and isresponsible for association of PSCDs with membranes. Members ofthis family appear to mediate the regulation of protein sorting andmembrane trafficking. This gene is highly expressed in naturalkiller and peripheral T cells, and regulates the adhesiveness ofintegrins at the plasma membrane of lymphocytes. The encodedprotein is 83% homologous to that of CYTH2.
Other Names:
Cytohesin-1, PH, SEC7 and coiled-coil domain-containing protein 1, SEC7 homolog B2-1, CYTH1, D17S811E, PSCD1
Gene Name: CYTH1 (HGNC:9501)
Gene ID: 9267
Primary Accession: Q15438
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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