Cytochrome b Polyclonal Antibody

Background:
Cytochrome b is a component of the ubiquinol-cytochrome c reductase complex, which is a respiratory chain that generates an electrochemical potential, coupled to ATP synthesis. The principal components of the b-c1 complex are cytochrome b, cytochrome c1, and the rieske protein. Cytochrome b posesses two heme groups, which are not covalently attached to the protein. Mutations in cytochrome b are associated with Leber’s hereditary optic neuropathy and with myopathy.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
COB, Complex III subunit 3, Complex III subunit III, CYB, CYTB, Cytochrome b, Cytochrome b c1 complex subunit 3, Cytochrome b-c1 complex subunit 3, Mitochondrially encoded cytochrome b, MT-CYB, MTCYB, Ubiquinol cytochrome c reductase complex cytochrome b subunit, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit

Immunogen: Synthetic peptide of human MT-CYB

Swissprot: P00156
Gene Accession: YP_003024038

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.