Cytochrome P450 17A1 (clone 6E1-H9-F6), anti-human
€295.00
In stock
SKU
K000082M
Catalog Number: K000082M
Size: 100 μl
Other size: 50 μl
Isotype: Mouse IgG2b
Applications: WB
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Size: 100 μl
Other size: 50 μl
Isotype: Mouse IgG2b
Applications: WB
Request Manual
Questions? Contact us!
Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes.The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol,steroids and other lipids.This protein localizes to the endoplasmic reticulum.It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins,mineralocorticoids,glucocorticoids,androgens,and estrogens.Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency,17-alpha-hydroxylase/17,20-lyase deficiency,pseudohermaphroditism,and adrenal hyperplasia.[provided by RefSeq,Jul 2008]
Synonyms: CPT7, CYP17, P450C17, S17AH
Cellular Location: Membrane
Immunogen:
Purified recombinant human Cytochrome P450 17A1 protein fragments expressed in E.coli.
Gene Symbol: Cytochrome P450 17A1
Gene ID: 1586
Swiss prot: P05093
Calculated MW: 60kDa
Recommended dilution:
WB 1:1000
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
This gene encodes a member of the cytochrome P450 superfamily of enzymes.The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol,steroids and other lipids.This protein localizes to the endoplasmic reticulum.It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins,mineralocorticoids,glucocorticoids,androgens,and estrogens.Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency,17-alpha-hydroxylase/17,20-lyase deficiency,pseudohermaphroditism,and adrenal hyperplasia.[provided by RefSeq,Jul 2008]
Synonyms: CPT7, CYP17, P450C17, S17AH
Cellular Location: Membrane
Immunogen:
Purified recombinant human Cytochrome P450 17A1 protein fragments expressed in E.coli.
Gene Symbol: Cytochrome P450 17A1
Gene ID: 1586
Swiss prot: P05093
Calculated MW: 60kDa
Recommended dilution:
WB 1:1000
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
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