Cytochrome P450 2D6 polyclonal, anti-rat, mouse

Quantity: 100 µg

Background:
Cytochrome P450 2D6(CYP2D6) is one of the most important enzymes involved in the metabolism of xenobiotics in the body. It is a member of Cytochrome P450, family 2, subfamily D, polypeptide 6. Its gene is mapped to chromosome 22q13.1. It has got 497 amino acid proteins which shares 73% sequence identity with the rat protein. CYP2D6 is highly expressed in human liver. CYP2D6 is the major isozyme involved in the formation of N-hydroxyprocainamide, a metabolite potentially involved in the drug-induced lupus syndrome observed with procainamide

Description:
Rabbit IgG polyclonal antibody for Cytochrome P450 2D6 (CYP2D6) detection. Tested with WB, IHC-P in Mouse, Rat.

Synonyms:
CPD6 antibody, CYP2D antibody, CYP2D6 antibody, CYP2D7AP antibody, CYP2D7BP antibody, CYP2D7P2 antibody, CYP2D8P2 antibody, CYP2DL1 antibody, CYPIID6 antibody, Cytochrome P450 DB1 antibody, Cytochrome P450 family 2 subfamily D polypeptide 6 antibody, Debrisoquine 4 hydroxylase antibody, EC 1.14.14.1 antibody, Flavoprotein linked monooxygenase antibody, MGC120389 antibody, MGC120390 antibody, Microsomal monooxygenase antibody, P450 DB1 antibody, P450C2D antibody, P450DB1 antibody, Xenobiotic monooxygenase antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of mouse Cytochrome P450 2D6(194-214aa FACRFEYNDPRFIRLLDLLKD), identical to the related rat sequence.A synthetic peptide corresponding to a sequence in the middle region of mouse Cytochrome P450 2D6(194-214aa FACRFEYNDPRFIRLLDLLKD), identical to the related rat sequence.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: rat.
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.