Cytochrome P450 3A4 CYP3A4 monoclonal, anti-human

Description: Anti-Cytochrome P450 3A4 CYP3A4 Monoclonal Antibody . Tested in WB, IHC, IP applications. This antibody reacts with Human.

Other Names: Cytochrome P450 3A4, 1.14.14.1, 1,4-cineole 2-exo-monooxygenase, 1,8-cineole 2-exo-monooxygenase, 1.14.14.56, Albendazole monooxygenase (sulfoxide-forming), 1.14.14.73, Albendazole sulfoxidase, CYPIIIA3, CYPIIIA4, Cholesterol 25-hydroxylase, Cytochrome P450 3A3, Cytochrome P450 HLp, Cytochrome P450 NF-25, Cytochrome P450-PCN1, Nifedipine oxidase, Quinine 3-monooxygenase, 1.14.14.55, CYP3A4 {ECO:0000303|PubMed:11470997, ECO:0000312|HGNC:HGNC:2637}

Clone Name(s):
Clone: ACDE-3

Gene ID: 1576

Immunogen: A synthesized peptide derived from human Cytochrome P450 3A4 Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. The enzyme also hydroxylates etoposide.

Calculated MW: 57343

Purification: Affinity-chromatography

Format: Liquid

Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.