Cytokeratin 17, CK17B (clone C58), anti-human, mouse, rat
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In stock
SKU
BMA1015
Catalog Number: BMA1015
Size: 100 μg
Isotype: Mouse IgG2a
Reactivity: human, mouse, rat
Application(s): WB, IHC-P, ICC
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Size: 100 μg
Isotype: Mouse IgG2a
Reactivity: human, mouse, rat
Application(s): WB, IHC-P, ICC
Request Information
Background:
Cytokeratin 17, also known as Keratin, type I cytoskeletal 17 (K17) is a protein that in humans is encoded by the KRT17 gene. Keratin 17 (K17) is a differentiation-specific keratin expressed in the nail bed, hair follicle, sebaceous gland and other epidermal appendages.1The KRT17 gene is 5 kb long with 8 exons.Mutations in the gene encoding this protein lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. Cytokeratin 17 synthesis seems to be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells".2
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to the N-terminal of mouse CK17.
Recommended Application:
Western Blot, WB(1:200-1:1, 000); Immunohistochemistry, IHC-P(1:50); Immunocytochemistry, ICC (1:50)
Product Form: Liquid
Purification: Peptide affinity purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
Cytokeratin 17, also known as Keratin, type I cytoskeletal 17 (K17) is a protein that in humans is encoded by the KRT17 gene. Keratin 17 (K17) is a differentiation-specific keratin expressed in the nail bed, hair follicle, sebaceous gland and other epidermal appendages.1The KRT17 gene is 5 kb long with 8 exons.Mutations in the gene encoding this protein lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. Cytokeratin 17 synthesis seems to be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells".2
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to the N-terminal of mouse CK17.
Recommended Application:
Western Blot, WB(1:200-1:1, 000); Immunohistochemistry, IHC-P(1:50); Immunocytochemistry, ICC (1:50)
Product Form: Liquid
Purification: Peptide affinity purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
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