Cytokeratin 17 (Keratin K17) (clone E3), anti-human, rat

Cytokeratin 17 (Keratin K17) (clone E3), anti-human, rat

€564.00
In stock
SKU
ARP-21-5049
Catalog Number: 21-5049
Size: 100 µg
Isotype: Mouse IgG2b
Background:
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in Human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 – 7.8. The individual Human Cytokeratins are numbered 1 to 20. The various epithelia in the Human body usually express Cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of matuRation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The Cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

Clone: E3

Isotype: Mouse IgG2b

Source: E3 is a Mouse monoclonal IgG2b antibody derived by fusion of X63 Ag 8.653 Mouse myeloma cells with spleen cells from a Balb/c Mouse immunized with a cytoskeletal prepaRation from Rat colon.

Reactivity: human, rat

Specificity: E3 reacts with Cytokeratin 17 in basal layers of pseudo-stRatified and transitional epithelia.

Form: Each vial contains 100 ug 1 mg/ml purified monoclonal antibody in PBS 0.02% sodium azide.

Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Western blotting

Storage: Store at 4C, or in small aliquots at -20C.
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