Cytokeratin 18 Rabbit pAb

Background:
Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood. 

Cellular localization: Cytoplasm, Intermediate filament, Keratin, Nucleus

Specificity: Human

Alternative Names:
Cell proliferation inducing gene 46 protein, CK 18, CYK 18, K 18, Keratin 18, Ketatin D, KRT18

Immunogen: Recombinant Protein

Isotype: Rabbit Polyclonal IgG

Concentration: 1mg/ml

Recommended dilutions: WB 1:1,000-2,000, IHC 1:500-1,000

Observed band: 46kDa

GeneID: 3875

Swiss-Prot No.: P05783

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Store at -20°C. Avoid repeated freeze-thaw cycles.

NOTE: For Research Use Only