Cytokeratin 19 (Keratin K19) (clone Ks 19.2 (Z105.6)), anti-human, rat, rabbit, bovine, fish, not with mouse, chicken, xenopus
€214.00
In stock
SKU
ARP-03-61029
Catalog Number: 03-61029
Size: 200 µl
Isotype: Mouse IgG2b
Size: 200 µl
Isotype: Mouse IgG2b
Background:
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
Decription:
Ks 19.2 represents an excellent marker to discriminate simple epithelial carcinoma from those of different origin. Polypeptide Reacting: Mr 40 000 polypeptide (keratin K19; formerly also designated cytokeratin 19) of human glandular epithelia. The epitope has been localized on aa. 352-368 (VRADSERQNQEYQRLMD) of the alpha-helical fragment.
Synonyms: K19, CK19, K1CS
Clone: Ks 19.2 (Z105.6)
Isotype: Mouse IgG2b
Immunogen: Cytokeratin/Keratin K19 of Mr 40000; from cultured human MCF-7 cells
Reactivity: human, rat, rabbit, bovine, fish, not with mouse, chicken, xenopus
Specificity: All tested adenocarcinoma; cholangio ca. of liver; renal cell ca.; transitional cell ca. of the bladder; ovary ca.; squamous cell ca. of cervix, bronchus and lung (intermediate type); mesothelioma; carcinoid tumor of bronchus; breast ca.; thymoma.
Form: Purified (Protein A), in PBS containing 1% BSA and 0.1% sodium-azide
Applications: Suitable for frozen tissue, Cytological material, Immunoblotting (Western)
Working Dilution: Dilute further to 1:10 (immunohistochemistry)
Reactivity: Reactivities cultured cell lines: MCF-7, RT 112, Detroit 562, RPMI 2650, HT-29, SSC-12
Storage: 2-8C for immediate use, or at -20C (aliquot)
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
Decription:
Ks 19.2 represents an excellent marker to discriminate simple epithelial carcinoma from those of different origin. Polypeptide Reacting: Mr 40 000 polypeptide (keratin K19; formerly also designated cytokeratin 19) of human glandular epithelia. The epitope has been localized on aa. 352-368 (VRADSERQNQEYQRLMD) of the alpha-helical fragment.
Synonyms: K19, CK19, K1CS
Clone: Ks 19.2 (Z105.6)
Isotype: Mouse IgG2b
Immunogen: Cytokeratin/Keratin K19 of Mr 40000; from cultured human MCF-7 cells
Reactivity: human, rat, rabbit, bovine, fish, not with mouse, chicken, xenopus
Specificity: All tested adenocarcinoma; cholangio ca. of liver; renal cell ca.; transitional cell ca. of the bladder; ovary ca.; squamous cell ca. of cervix, bronchus and lung (intermediate type); mesothelioma; carcinoid tumor of bronchus; breast ca.; thymoma.
Form: Purified (Protein A), in PBS containing 1% BSA and 0.1% sodium-azide
Applications: Suitable for frozen tissue, Cytological material, Immunoblotting (Western)
Working Dilution: Dilute further to 1:10 (immunohistochemistry)
Reactivity: Reactivities cultured cell lines: MCF-7, RT 112, Detroit 562, RPMI 2650, HT-29, SSC-12
Storage: 2-8C for immediate use, or at -20C (aliquot)
| Is Featured? | No |
|---|
Write Your Own Review