Cytokeratin 8/18 (clone C-43 + DC10 ), anti-human
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In stock
SKU
AC-AH13055
Catalog Number: AC-AH13055
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: C-43 + DC10
Applications: WB, IHC, IF, FC
Datasheet
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Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: C-43 + DC10
Applications: WB, IHC, IF, FC
Datasheet
Request Information
Background:
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.ĀImmunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.
Other Names:
Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8, KRT8, CYK8
Gene Name: KRT8
Gene ID: 3856
Primary Accession: P05787
Other Accession: 3856 (CK8), 3875 (CK18), 533782, 708445 (CK8), 406013 (CK18),P05783 (CK18)
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.ĀImmunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.
Other Names:
Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8, KRT8, CYK8
Gene Name: KRT8
Gene ID: 3856
Primary Accession: P05787
Other Accession: 3856 (CK8), 3875 (CK18), 533782, 708445 (CK8), 406013 (CK18),P05783 (CK18)
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