Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) (clone SPM116 ), anti-human, mouse, rat, rabbit, primate, chicken, bovine, D
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SKU
AC-AH10973
Catalog Number: AC-AH10973
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPM116
Applications: WB, IHC-P, IF, FC
Datasheet
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Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPM116
Applications: WB, IHC-P, IF, FC
Datasheet
Request Information
Background:
This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50’, 48, 46, 45, and 40kDa. This MAb recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
Other Names:
Keratin, type II cytoskeletal 2 oral, Cytokeratin-2P, CK-2P, K2P, Keratin-76, K76, Type-II keratin Kb9, KRT76, KRT2B, KRT2P
Gene Name: KRT76
Gene ID: 51350
Primary Accession: Q01546
Other Accession: 51350, 654392
This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50’, 48, 46, 45, and 40kDa. This MAb recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
Other Names:
Keratin, type II cytoskeletal 2 oral, Cytokeratin-2P, CK-2P, K2P, Keratin-76, K76, Type-II keratin Kb9, KRT76, KRT2B, KRT2P
Gene Name: KRT76
Gene ID: 51350
Primary Accession: Q01546
Other Accession: 51350, 654392
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