Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) (clone SPM591 ), anti-human, mouse, rat

Background:
This antibody recognizes CK1, CK5, CK10 and CK14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. This MAb shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands; there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this antibody. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. This antibody has also been useful in separating benign from malignant intraductal breast proliferations.

Other Names:
Keratin, type II cytoskeletal 1, 67 kDa cytokeratin, Cytokeratin-1, CK-1, Hair alpha protein, Keratin-1, K1, Type-II keratin Kb1, KRT1, KRTA

Gene Name: KRT1
Gene ID: 3848
Primary Accession: P04264
Other Accession: 3848 (CK1), 3852 (CK5), 3858 (CK10), 3861 (CK14),P13647 (CK5),P13645 (CK10),P02533 (CK14)