Cytokeratin/Keratin PAN polyclonal, anti-human, mouse

Quantity: 25 µl

Background:
Cytokeratins are precisely regulated in tissue and little is known about the molecular mechanisms underlying this regulation. However, the expression pattern of cytokeratin 6 is known to be particularly complex. It is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations.

Isotype: Guinea Pig Polyclonal

Immunogen:
Synthetic peptides of human keratins

Form: Stabilized Serum

Specificity:
Acidic (K1, K4, K8) and basic (K14) keratins (Mr 40,000 Mr 68,000 polypeptides). Tumors specifically detected: All types of epithelia and epithelium-derived neoplasms.

Reactivity: human, mouse

Applications: Immunohistochemistry on frozen & paraffin sections, Immunoblotting (Western)

Working DIlution: 1:100 for immunohistochemistry on frozen sections, 1:50 for paraffin, 1:2000 for Western blotting

Storage: 2-8C

References:
- Boehnke k et al. (2007) Eur J Cell Biol 86: 731-746