Cytokeratin Peptide 18 (clone CY-90), anti-human, rat
€455.00
In stock
SKU
AC-ABO10420
Catalog Number: AC-ABO10420
Size: 100 µg
Isotype: Mouse IgG
Applications: WB, IHC-P, IHC-F
Datasheet
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Size: 100 µg
Isotype: Mouse IgG
Applications: WB, IHC-P, IHC-F
Datasheet
Request Information
Description: Mouse IgG monoclonal antibody for Cytokeratin Peptide 18, keratin 18 (KRT18) detection. Tested with WB, IHC-P, IHC-F in Human; rat. No cross reactivity with other proteins.Protein Name: Keratin, type I cytoskeletal 18
Protein Function:
When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection (By similarity). Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. .
Other Names: Keratin, type I cytoskeletal 18, Cytokeratin-18, CK-18, Keratin-18, K18, Krt18 {ECO:0000250|UniProtKB:P05783}
Clone Name(s):
CY-90
Subcellular Localization: Nucleus matrix . Nucleus, nucleolus . Cytoplasm .
Tissue Specificity: Expressed on the plasma membrane of hepatocytes and in the narrow apical portions of supporting cells in the vomeronasal sensory epithelium. Detected in the type III alveolar cells of the lung, in the proliferative crypt epithelium of the small intestine and in the older intragemmal cells of the tongue. .
Gene ID: 294853
Immunogen: The human epidermal carcinoma A-431 and MCF-7 human breast cancer cell lines.
Calculated MW: 47761
Purification: Ascites
Format: Lyophilized
Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Contents: Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Concentration (mg/ml): Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Function:
When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection (By similarity). Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. .
Other Names: Keratin, type I cytoskeletal 18, Cytokeratin-18, CK-18, Keratin-18, K18, Krt18 {ECO:0000250|UniProtKB:P05783}
Clone Name(s):
CY-90
Subcellular Localization: Nucleus matrix . Nucleus, nucleolus . Cytoplasm .
Tissue Specificity: Expressed on the plasma membrane of hepatocytes and in the narrow apical portions of supporting cells in the vomeronasal sensory epithelium. Detected in the type III alveolar cells of the lung, in the proliferative crypt epithelium of the small intestine and in the older intragemmal cells of the tongue. .
Gene ID: 294853
Immunogen: The human epidermal carcinoma A-431 and MCF-7 human breast cancer cell lines.
Calculated MW: 47761
Purification: Ascites
Format: Lyophilized
Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Contents: Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Concentration (mg/ml): Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
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