DAAM1 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP2720a
Background:
Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton. Recent evidence suggests a role for the Formin homology (FH) proteins in these processes. DAAM1 contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by DAAM1, which is thought to function as a scaffolding protein.
Other Names:
Disheveled-associated activator of morphogenesis 1, DAAM1, KIAA0666
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2720a was selected from the N-term region of humanAM1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: DAAM1
Gene ID: 23002
Primary Accession: Q9Y4D1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton. Recent evidence suggests a role for the Formin homology (FH) proteins in these processes. DAAM1 contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by DAAM1, which is thought to function as a scaffolding protein.
Other Names:
Disheveled-associated activator of morphogenesis 1, DAAM1, KIAA0666
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2720a was selected from the N-term region of humanAM1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: DAAM1
Gene ID: 23002
Primary Accession: Q9Y4D1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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