DAAM1 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP2720b
Catalog Number: AC-AP2720b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB10612
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB10612
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. DAAM1 contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by DAAM1, which is thought to function as a scaffolding protein.
Other Names:
Disheveled-associated activator of morphogenesis 1, DAAM1, KIAA0666
Target/Specificity:
This DAAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1034-1063 amino acids from the C-terminal region of human DAAM1.
Antigen Region:
1034-1063
Antigen Type: Synthetic Peptide
Gene Name: DAAM1
Gene ID: 23002
Primary Accession: Q9Y4D1
NCBI Accession: NP_001257449.1;NP_055807.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. DAAM1 contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by DAAM1, which is thought to function as a scaffolding protein.
Other Names:
Disheveled-associated activator of morphogenesis 1, DAAM1, KIAA0666
Target/Specificity:
This DAAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1034-1063 amino acids from the C-terminal region of human DAAM1.
Antigen Region:
1034-1063
Antigen Type: Synthetic Peptide
Gene Name: DAAM1
Gene ID: 23002
Primary Accession: Q9Y4D1
NCBI Accession: NP_001257449.1;NP_055807.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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