DAAM1-T361 polyclonal (N-term), anti-human, hamster
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In stock
SKU
AC-AP5439a
Catalog Number: AC-AP5439a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB15348
Applications: FC, IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB15348
Applications: FC, IHC-P, WB
Datasheet
Request Information
Background:
Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.
Other Names:
Disheveled-associated activator of morphogenesis 1, DAAM1, KIAA0666
Target/Specificity:
This DAAM1-T361 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the N-terminal region of human DAAM1-T361.
Antigen Region:
341-370
Antigen Type: Synthetic Peptide
Gene Name: DAAM1
Gene ID: 23002
Primary Accession: Q9Y4D1
NCBI Accession: NP_001257449.1;NP_055807.1
Other Accession: NP_055807.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.
Other Names:
Disheveled-associated activator of morphogenesis 1, DAAM1, KIAA0666
Target/Specificity:
This DAAM1-T361 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the N-terminal region of human DAAM1-T361.
Antigen Region:
341-370
Antigen Type: Synthetic Peptide
Gene Name: DAAM1
Gene ID: 23002
Primary Accession: Q9Y4D1
NCBI Accession: NP_001257449.1;NP_055807.1
Other Accession: NP_055807.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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