Dab1 (Phospho-Tyr220) Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice| the disabled-1 gene plays a central role in brain development| directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1| and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported| but their full length nature has not been determined.

Research Area: Neuroscience, Signal transduction

Synonyms: Dab1 , Tyr220, Disabled homolog 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year