DACH2 Polyclonal Antibody

Background:
This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
DACH 2, Dach2, DACH2, Dachshund 2, Dachshund homolog 2 (Drosophila), Dachshund homolog 2, Dachshund2, FLJ31391 , HGNC:16814, MGC138545

Immunogen: Recombinant protein of human DACH2

Swissprot: Q96NX9
Gene Accession: BC114950

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-74392/sc-74394