DAF antibody (clone 1G3), anti-human
€435.00
In stock
SKU
AC-AT1709a
Catalog Number: AC-AT1709a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
Request Information AC-AT1709a">Request Information
Background:
This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Other Names:
Complement decay-accelerating factor, CD55, CD55, CR, DAF
Antigen Type:
Recombinant Protein
Gene Name: CD55
Gene ID: 1604
NCBI Accession: NP_000565.1;NP_001108224.1
Primary Accession: P08174
Other Accession: NM_000574
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Other Names:
Complement decay-accelerating factor, CD55, CD55, CR, DAF
Antigen Type:
Recombinant Protein
Gene Name: CD55
Gene ID: 1604
NCBI Accession: NP_000565.1;NP_001108224.1
Primary Accession: P08174
Other Accession: NM_000574
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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