DAG1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.

Synonyms: 156DAG, A3a, AGRNR, DAG, MDDGA9, MDDGC7, MDDGC9

Cellular Location: Cell junction Cell membrane Cytoplasm Nucleus Secreted Single-pass type I membrane protein cytoskeleton extracellular space nucleoplasm postsynaptic cell membrane sarcolemma synapse

Immunogen:
Recombinant protein of human DAG1

Gene Symbol: DAG1

Gene ID: 1605

Swiss prot: Q14118

Calculated MW: 97kDa

Recommended dilution:
WB 1:500-1000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.