DAP10 / HCST polyclonal, anti-human

Background:
This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms.

Other Names:
Hematopoietic cell signal transducer, DNAX-activation protein 10, Membrane protein DAP10, Transmembrane adapter protein KAP10, HCST, DAP10, KAP10, PIK3AP

Antigen Types:
Synthetic Peptide

Gene Name:
HCST
Gene ID:
10870
Primary Accession: Q9UBK5
Other Accession: NP_001007470;10870;23900 (mouse); 474146 (rat);