DAPK3 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP7125b
Background:
Death-associated protein kinase 3 (DAPK3) induces morphological changes in apoptosis when overexpressed in mammalian cells. These results suggest that DAPK3 may play a role in the induction of apoptosis. DAPK3 fors a homodimer or heterodimers with ATF4. Both interactions require an intact leucine zipper domain and oligomerization is required for full enzymatic activity. DAPK3 Also binds to DAXX and PAWR, possibly in a ternary complex which plays a role in caspase activation. This protein interacts with AATF and CDC5L.
Other Names:
Death-associated protein kinase 3, DAP kinase 3, DAP-like kinase, Dlk, MYPT1 kinase, Zipper-interacting protein kinase, ZIP-kinase, DAPK3, ZIPK
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7125b was selected from the Center region of humanPK3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: DAPK3
Gene ID: 1613
Primary Accession: O43293
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Death-associated protein kinase 3 (DAPK3) induces morphological changes in apoptosis when overexpressed in mammalian cells. These results suggest that DAPK3 may play a role in the induction of apoptosis. DAPK3 fors a homodimer or heterodimers with ATF4. Both interactions require an intact leucine zipper domain and oligomerization is required for full enzymatic activity. DAPK3 Also binds to DAXX and PAWR, possibly in a ternary complex which plays a role in caspase activation. This protein interacts with AATF and CDC5L.
Other Names:
Death-associated protein kinase 3, DAP kinase 3, DAP-like kinase, Dlk, MYPT1 kinase, Zipper-interacting protein kinase, ZIP-kinase, DAPK3, ZIPK
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7125b was selected from the Center region of humanPK3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: DAPK3
Gene ID: 1613
Primary Accession: O43293
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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