DAZ2 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12295b
Background:
This gene is a member of the DAZ gene family and is acandidate for the human Y-chromosomal azoospermia factor (AZF). Itsexpression is restricted to premeiotic germ cells, particularly inspermatogonia. It encodes an RNA-binding protein that is importantfor spermatogenesis. Four copies of this gene are found onchromosome Y within palindromic duplications; one pair of genes ispart of the P2 palindrome and the second pair is part of the P1palindrome. Each gene contains a 2.4 kb repeat including a 72-bpexon, called the DAZ repeat; the number of DAZ repeats is variableand there are several variations in the sequence of the DAZ repeat.Each copy of the gene also contains a 10.8 kb region that may beamplified; this region includes five exons that encode an RNArecognition motif (RRM) domain. This gene contains one copy of the10.8 kb repeat. Alternative splicing results in multiple transcriptvariants encoding different isoforms.
Other Names:
Deleted in azoospermia protein 2, DAZ2
Gene Name: DAZ2
Gene ID: 57055
Primary Accession: Q13117
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene is a member of the DAZ gene family and is acandidate for the human Y-chromosomal azoospermia factor (AZF). Itsexpression is restricted to premeiotic germ cells, particularly inspermatogonia. It encodes an RNA-binding protein that is importantfor spermatogenesis. Four copies of this gene are found onchromosome Y within palindromic duplications; one pair of genes ispart of the P2 palindrome and the second pair is part of the P1palindrome. Each gene contains a 2.4 kb repeat including a 72-bpexon, called the DAZ repeat; the number of DAZ repeats is variableand there are several variations in the sequence of the DAZ repeat.Each copy of the gene also contains a 10.8 kb region that may beamplified; this region includes five exons that encode an RNArecognition motif (RRM) domain. This gene contains one copy of the10.8 kb repeat. Alternative splicing results in multiple transcriptvariants encoding different isoforms.
Other Names:
Deleted in azoospermia protein 2, DAZ2
Gene Name: DAZ2
Gene ID: 57055
Primary Accession: Q13117
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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