DAZ2 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP12295b
Catalog Number: AC-AP12295b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31061
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31061
Applications: WB
Datasheet
Request Information
Background:
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.
Other Names:
Deleted in azoospermia protein 2, DAZ2
Target/Specificity:
This DAZ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-546 amino acids from the C-terminal region of human DAZ2.
Antigen Region:
518-546
Antigen Type: Synthetic Peptide
Gene Name: DAZ2
Gene ID: 57055
Primary Accession: Q13117
NCBI Accession: NP_001005785.1;NP_001005786.2;NP_065096.2
Other Accession: Q86SG3; Q9NR90; Q9NQZ3; NP_001005785.1; NP_065096.1; NP_001005786.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.
Other Names:
Deleted in azoospermia protein 2, DAZ2
Target/Specificity:
This DAZ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-546 amino acids from the C-terminal region of human DAZ2.
Antigen Region:
518-546
Antigen Type: Synthetic Peptide
Gene Name: DAZ2
Gene ID: 57055
Primary Accession: Q13117
NCBI Accession: NP_001005785.1;NP_001005786.2;NP_065096.2
Other Accession: Q86SG3; Q9NR90; Q9NQZ3; NP_001005785.1; NP_065096.1; NP_001005786.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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