DAZ3 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP12305b
Catalog Number: AC-AP12305b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31085
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31085
Applications: IHC-P, WB
Datasheet
Request Information
Background:
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat.
Other Names:
Deleted in azoospermia protein 3, DAZ3
Target/Specificity:
This DAZ3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human DAZ3.
Antigen Region:
445-474
Antigen Type: Synthetic Peptide
Gene Name: DAZ3
Gene ID: 57054
Primary Accession: Q9NR90
NCBI Accession: NP_065097.2
Other Accession: Q86SG3; Q13117; Q9NQZ3; NP_065097.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat.
Other Names:
Deleted in azoospermia protein 3, DAZ3
Target/Specificity:
This DAZ3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human DAZ3.
Antigen Region:
445-474
Antigen Type: Synthetic Peptide
Gene Name: DAZ3
Gene ID: 57054
Primary Accession: Q9NR90
NCBI Accession: NP_065097.2
Other Accession: Q86SG3; Q13117; Q9NQZ3; NP_065097.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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