DAZ4 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP12556c
Background:
This gene is a member of the DAZ gene family and is acandidate for the human Y-chromosomal azoospermia factor (AZF). Itsexpression is restricted to premeiotic germ cells, particularly inspermatogonia. It encodes an RNA-binding protein that is importantfor spermatogenesis. Four copies of this gene are found onchromosome Y within palindromic duplications; one pair of genes ispart of the P2 palindrome and the second pair is part of the P1palindrome. Each gene contains a 2.4 kb repeat including a 72-bpexon, called the DAZ repeat; the number of DAZ repeats is variableand there are several variations in the sequence of the DAZ repeat.Each copy of the gene also contains a 10.8 kb region that may beamplified; this region includes five exons that encode an RNArecognition motif (RRM) domain. This gene contains two copies ofthe 10.8 kb repeat. Alternative splicing results in multipletranscript variants encoding different isoforms. [provided byRefSeq].
Other Names:
Deleted in azoospermia protein 4, DAZ4
Gene Name: DAZ4
Gene ID: 57135
Primary Accession: Q86SG3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene is a member of the DAZ gene family and is acandidate for the human Y-chromosomal azoospermia factor (AZF). Itsexpression is restricted to premeiotic germ cells, particularly inspermatogonia. It encodes an RNA-binding protein that is importantfor spermatogenesis. Four copies of this gene are found onchromosome Y within palindromic duplications; one pair of genes ispart of the P2 palindrome and the second pair is part of the P1palindrome. Each gene contains a 2.4 kb repeat including a 72-bpexon, called the DAZ repeat; the number of DAZ repeats is variableand there are several variations in the sequence of the DAZ repeat.Each copy of the gene also contains a 10.8 kb region that may beamplified; this region includes five exons that encode an RNArecognition motif (RRM) domain. This gene contains two copies ofthe 10.8 kb repeat. Alternative splicing results in multipletranscript variants encoding different isoforms. [provided byRefSeq].
Other Names:
Deleted in azoospermia protein 4, DAZ4
Gene Name: DAZ4
Gene ID: 57135
Primary Accession: Q86SG3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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