DAZ4 polyclonal (Center), anti-human
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In stock
SKU
AC-AP12556c
Catalog Number: AC-AP12556c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31069
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31069
Applications: IHC-P, WB
Datasheet
Request Information
Background:
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains two copies of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
Other Names:
Deleted in azoospermia protein 4, DAZ4
Target/Specificity:
This DAZ4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the Central region of human DAZ4.
Antigen Region:
90-119
Antigen Type: Synthetic Peptide
Gene Name: DAZ4
Gene ID: 57135
Primary Accession: Q86SG3
NCBI Accession: NP_001005375.1;NP_065153.1
Other Accession: Q9NR90; Q13117; Q9NQZ3; NP_001005375.1; NP_065153.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains two copies of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
Other Names:
Deleted in azoospermia protein 4, DAZ4
Target/Specificity:
This DAZ4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the Central region of human DAZ4.
Antigen Region:
90-119
Antigen Type: Synthetic Peptide
Gene Name: DAZ4
Gene ID: 57135
Primary Accession: Q86SG3
NCBI Accession: NP_001005375.1;NP_065153.1
Other Accession: Q9NR90; Q13117; Q9NQZ3; NP_001005375.1; NP_065153.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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