DAZL/SPGYLA/TPX2 Polyclonal, anti-human, rat, mouse, bovine

Description: DAZL (Deleted in azoospermia-like 1; SPGY-like-autosomal) is an RNA-binding protein that interacts with mRNA transcripts by its N-terminal RNA recognition motifs. It is the product of the Y-linked DAZ gene, and is found exclusively in the testes. DAZL regulates gene expression during spermatogenesis and may shuttle between the nucleus and cytoplasm during various stages of this process. It interacts with other proteins of the DAZ family via its DAZ-like domain, including DAZ, BOLL, DAZAP1, DAZAP2, and PUM2. Disruption of DAZL expression may play a role in male infertility.Localization: cytoplasm, nucleusDilution: 25-50Positive Control: Testis whole tissue lysateHIER: citrate pH6.0 or EDTA pH8.0Status: RUO