DCC Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP12334c
Background:
This gene encodes a netrin 1 receptor. The transmembraneprotein is a member of the immunoglobulin superfamily of celladhesion molecules, and mediates axon guidance of neuronal growthcones towards sources of netrin 1 ligand. The cytoplasmic tailinteracts with the tyrosine kinases Src and focal adhesion kinase(FAK, also known as PTK2) to mediate axon attraction. The proteinpartially localizes to lipid rafts, and induces apoptosis in theabsence of ligand. The protein functions as a tumor suppressor, andis frequently mutated or downregulated in colorectal cancer andesophageal carcinoma.
Other Names:
Netrin receptor DCC, Colorectal cancer suppressor, Immunoglobulin superfamily DCC subclass member 1, Tumor suppressor protein DCC, DCC, IGDCC1
Gene Name: DCC
Gene ID: 1630
Primary Accession: P43146
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a netrin 1 receptor. The transmembraneprotein is a member of the immunoglobulin superfamily of celladhesion molecules, and mediates axon guidance of neuronal growthcones towards sources of netrin 1 ligand. The cytoplasmic tailinteracts with the tyrosine kinases Src and focal adhesion kinase(FAK, also known as PTK2) to mediate axon attraction. The proteinpartially localizes to lipid rafts, and induces apoptosis in theabsence of ligand. The protein functions as a tumor suppressor, andis frequently mutated or downregulated in colorectal cancer andesophageal carcinoma.
Other Names:
Netrin receptor DCC, Colorectal cancer suppressor, Immunoglobulin superfamily DCC subclass member 1, Tumor suppressor protein DCC, DCC, IGDCC1
Gene Name: DCC
Gene ID: 1630
Primary Accession: P43146
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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