DCK Polyclonal Antibody
€0.00
In stock
SKU
E-AB-14732
Catalog Number: E-AB-14732
Isotype: Rabbit IgG
Reactivity: human, mouse, rat
Applications: WB,ELISA
Datasheet, Questions? Contact us!
Isotype: Rabbit IgG
Reactivity: human, mouse, rat
Applications: WB,ELISA
Datasheet, Questions? Contact us!
Background:
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Research Area: Cancer, Signal Transduction
Synonyms:
dCK, DCK protein, DCK, Deoxycytidine kinase, Deoxynucleoside kinase, EC 2.7.1, EC 2.7.1.74, MGC117410, MGC138632, OTTHUMP00000219118, OTTHUMP00000219119
Immunogen: Recombinant protein of human DCK
Swissprot: P27707
Gene Accession: BC114617
Calculated MW: 31 kDa
Purification Method: Affinity purification
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration: 0.3 mg/mL
Dilution: WB 1:200-1:1000
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Alternative for product with catalog number:
sc-49283/sc-49284/sc-49285/sc-99008
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Research Area: Cancer, Signal Transduction
Synonyms:
dCK, DCK protein, DCK, Deoxycytidine kinase, Deoxynucleoside kinase, EC 2.7.1, EC 2.7.1.74, MGC117410, MGC138632, OTTHUMP00000219118, OTTHUMP00000219119
Immunogen: Recombinant protein of human DCK
Swissprot: P27707
Gene Accession: BC114617
Calculated MW: 31 kDa
Purification Method: Affinity purification
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration: 0.3 mg/mL
Dilution: WB 1:200-1:1000
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Alternative for product with catalog number:
sc-49283/sc-49284/sc-49285/sc-99008
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