DCK polyclonal (C-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP7087B
Catalog Number: AC-AP7087B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB05276
Applications: IP, WB, IF, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB05276
Applications: IP, WB, IF, IHC-P
Datasheet
Request Information
Background:
Deoxycytidine kinase is responsible for the phosphorylation of several deoxyribonucleosides and their analogs. Deficiency of this enzyme activity is associated with resistance to antiviral and anticancer chemotherapeutic agents, whereas increased enzyme activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. It is the rate limiting enzyme in the activation of many important anticancer and retroviral drugs and its activity is often decreased in cells that are resistant to cytosine arabinoside.
Other Names:
Deoxycytidine kinase, dCK, DCK
Target/Specificity:
This DCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-200 amino acids from the C-terminal region of human DCK.
Antigen Region:
171-200
Antigen Type: Synthetic Peptide
Gene Name: DCK
Gene ID: 1633
Primary Accession: P27707
NCBI Accession: NP_000779.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Deoxycytidine kinase is responsible for the phosphorylation of several deoxyribonucleosides and their analogs. Deficiency of this enzyme activity is associated with resistance to antiviral and anticancer chemotherapeutic agents, whereas increased enzyme activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. It is the rate limiting enzyme in the activation of many important anticancer and retroviral drugs and its activity is often decreased in cells that are resistant to cytosine arabinoside.
Other Names:
Deoxycytidine kinase, dCK, DCK
Target/Specificity:
This DCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-200 amino acids from the C-terminal region of human DCK.
Antigen Region:
171-200
Antigen Type: Synthetic Peptide
Gene Name: DCK
Gene ID: 1633
Primary Accession: P27707
NCBI Accession: NP_000779.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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