DCLRE1C Polyclonal Antibody

Background:
This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants.

Synonyms:
DCLRE1C, A-SCID, DCLREC1C, RS-SCID, SCIDA, SNM1C

Immunogen: Recombinant fusion protein of human DCLRE1C (NP_001029027.1).

Swissprot: Q96SD1
Gene ID: 64421

Calculated MW: 49 kDa/64 kDa/65 kDa/78 kDa
Observed MW: 45 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.