DCN Polyclonal Antibody

Background:
This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients.

Research Area: Cancer, Signal Transduction, Stem Cells

Synonyms:
DCN, CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B, decorin, Decorin

Immunogen: Recombinant fusion protein of human DCN (NP_598010.1).

Swissprot: P07585
Gene ID: 1634

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.