DCP1A polyclonal, anti-human, mouse

Protein Family: Enzymes, Chaperones and Folding Catalysts

Pathway and Disease: Folding, Sorting and Degradation

Description:
mRNA-decapping enzyme 1A (Dcp1A) is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Dcp1A removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Dcp1A contributes to the transactivation of target genes after stimulation by TGFB1.

Alternate Names: mRNA-decapping enzyme 1A, Transcription factor SMIF, Smad4-interacting transcriptional co-activator, DCP1A, SMIF

Application Notes: E: 1:10,000-1:50,000; WB: 1:200-1:1,000; IHC: 1:50-1:250

Accession No.: Q9NPI6

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Dcp1A.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purifiedby immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.