DCP2 Polyclonal Antibody

Background:
The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
DCP2, DCP2 decapping enzyme homolog (S. cerevisiae), DCP2, S. cerevisiae, homolog of, DCP2, decapping enzyme 2, S. cerevisiae, homolog of, decapping enzyme homolog (S. cerevisiae), FLJ33245, hDpc, m7GpppN-mRNA hydrolase, mRNA decapping enzyme 2, mRNA-decapping enzyme 2, Nucleoside diphosphate-linked moiety X motif 20, nudix (nucleoside diphosphate linked moiety X)-type motif 20, Nudix motif 20, NUDT20

Immunogen: Fusion protein of human DCP2

Swissprot: Q8IU60
Gene Accession: BC064593

Calculated MW: 48 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.