DCPS Polyclonal Antibody
€0.00
In stock
SKU
E-AB-65756
Catalog Number: E-AB-65756
Isotype: Rabbit IgG
Reactivity: human
Applications: WB
Datasheet, Questions? Contact us!
Isotype: Rabbit IgG
Reactivity: human
Applications: WB
Datasheet, Questions? Contact us!
Background:
This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5′ mRNA cap structure, which appear in the 3′ → 5′ mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover.
Synonyms:
DCPS, ARS, DCS1, HINT-5, HINT5, HSL1, HSPC015
Immunogen: Recombinant fusion protein of human DCPS (NP_054745.1).
Swissprot: Q96C86
Gene ID: 28960
Calculated MW: 38 kDa
Observed MW: 38 kDa
Purification Method: Affinity purification
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration: 1 mg/mL
Dilution: "WB 1:1000-1:2000"
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5′ mRNA cap structure, which appear in the 3′ → 5′ mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover.
Synonyms:
DCPS, ARS, DCS1, HINT-5, HINT5, HSL1, HSPC015
Immunogen: Recombinant fusion protein of human DCPS (NP_054745.1).
Swissprot: Q96C86
Gene ID: 28960
Calculated MW: 38 kDa
Observed MW: 38 kDa
Purification Method: Affinity purification
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration: 1 mg/mL
Dilution: "WB 1:1000-1:2000"
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
| Is Featured? | No |
|---|
Write Your Own Review