Dcr-1 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP1961c
Background:
The Dcr-1 gene encodes a bidentate ribonuclease that is homologous to E. coli RNAse III. Dcr-1 is required both for RNA interference and for synthesis of small developmental RNAs. Dcr-1 interacts in vivo with RDE-4, a double-stranded RNA (dsRNA) binding protein required for RNAi that interacts with trigger dsRNAs and may function to deliver dsRNAs to Dcr-1 for endonucleolytic processing.
Other Names:
Endoribonuclease dcr-1, 3126-, dcr-1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1961c was selected from the Center region of human Dcr-1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: dcr-1 {ECO:0000303|PubMed:11641272, ECO:0000312|WormBase:K12H4.8}
Gene ID: 176138
Primary Accession: P34529
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The Dcr-1 gene encodes a bidentate ribonuclease that is homologous to E. coli RNAse III. Dcr-1 is required both for RNA interference and for synthesis of small developmental RNAs. Dcr-1 interacts in vivo with RDE-4, a double-stranded RNA (dsRNA) binding protein required for RNAi that interacts with trigger dsRNAs and may function to deliver dsRNAs to Dcr-1 for endonucleolytic processing.
Other Names:
Endoribonuclease dcr-1, 3126-, dcr-1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1961c was selected from the Center region of human Dcr-1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: dcr-1 {ECO:0000303|PubMed:11641272, ECO:0000312|WormBase:K12H4.8}
Gene ID: 176138
Primary Accession: P34529
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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