DcR1 Polyclonal Antibody

Background:
TNF receptor superfamily member 10c(TNFRSF10C) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008],

Alternative Names:
TNFRSF10C, DCR1, LIT, TRAILR3, TRID, Tumor necrosis factor receptor superfamily member 10C, Antagonist decoy receptor for TRAIL/Apo-2L, Decoy TRAIL receptor without death domainDecoy receptor 1, DcR1,

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human TNFRSF10C. AA range:11-60

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 27

GeneID: TNFRSF10C

Storage: -20°C/1 year

NOTE: For Research Use Only