DCTN1 (clone 3D5-C6-D5), anti-human antibody
€295.00
In stock
SKU
AC-ABV12072-100
Catalog Number: AC-ABV12072-100
Size: 100 µg
Host: Mouse IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Mouse IgG
Applications: WB
Datasheet
Request Information
Background:
Plays a key role in dynein-mediated retrograde transport of vesicles and organelles along microtubules by recruiting and tethering dynein to microtubules. Binds to both dynein and microtubules providing a link between specific cargos, microtubules and dynein. Essential for targeting dynein to microtubule plus ends, recruiting dynein to membranous cargos and enhancing dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Can also act as a brake to slow the dynein motor during motility along the microtubule.
Other Names:
Dynactin subunit 1, 150 kDa dynein-associated polypeptide, DAP-150, DP-150, p135, p150-glued
Primary Accession: Q14203
Gene Name: DCTN1
Gene ID: 1639
Plays a key role in dynein-mediated retrograde transport of vesicles and organelles along microtubules by recruiting and tethering dynein to microtubules. Binds to both dynein and microtubules providing a link between specific cargos, microtubules and dynein. Essential for targeting dynein to microtubule plus ends, recruiting dynein to membranous cargos and enhancing dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Can also act as a brake to slow the dynein motor during motility along the microtubule.
Other Names:
Dynactin subunit 1, 150 kDa dynein-associated polypeptide, DAP-150, DP-150, p135, p150-glued
Primary Accession: Q14203
Gene Name: DCTN1
Gene ID: 1639
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